Next-generation sequencing in neuropathological diagnosis of infections of the nervous system
Steven L. Salzberg, Florian Breitwieser, Anupama Kumar, Haiping Hao, Peter Burger, Fausto J. Rodriguez, Michael Lim, Alfredo Quinones-Hinojosa, Gary L. Gallia, Jeffrey A. Tornheim, Michael T. Melia, Cynthia L. Sears, Carlos A. Pardo
This study evaluates the feasibility of next-generation sequencing for diagnosing CNS infections using brain and spinal cord biopsies, showing successful pathogen identification in three patients.
bioRxiv · Feb 9, 2016Genomics