Oxidative DNA Damage Drives Apoptotic Photoreceptor Loss in NMNAT1-Associated Inherited Retinal Degeneration: A Therapeutic Opportunity
Hanmeng Zhang, Kevin Valestil, Rossano M. Butcher, Eric A. Pierce
This study shows that oxidative DNA damage causes photoreceptor loss in NMNAT1-related retinal degeneration and that NAC treatment reduces damage and preserves vision.
Cell Death and Disease · Apr 2, 2026Peer-reviewedCell Biology