Production of sterile Atlantic salmon by germ cell ablation with antisense oligonucleotides
Helge Tveiten, Øivind Andersen, Jaya Kumari Swain, Hanne Johnsen, Maren Mommens, Krasimir Slanchev
This paper demonstrates the sterilization of Atlantic salmon embryos using antisense oligonucleotides targeting the dead end gene, resulting in germ cell-depleted fish with normal morphology but no gametes.
bioRxiv · Apr 14, 2023 · PreprintDevelopmental Biology