Author

Haohong Zhang

Huazhong University of Science and TechnologyPrimary ORCID profile (0000-0001-6267-4244 · 7 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Haohong ZhangiD7 papers · Huazhong University of Science and Technology

Biology Disciplines

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Bioinformatics· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:metagenomics· 4 Approach:deep learning· 3 Research Focus:benchmarking· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:transformer / foundation model· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

Kang NingiD· 4 shared Yuli Zhang· 4 shared Ronghua YangiD· 3 shared Zixin KangiD· 2 shared Jiayun Xiong· 1 shared Jin Han· 1 shared Kouyi Zhou· 1 shared Linfeng ZhaoiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersBioinformatics

Kang NingORCID

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Author profile →

4 papers

Recent·Most cited

MGM2 as a Multimodal Foundation Model for Microbial Community States and Responses

Haohong Zhang, Yuli Zhang, Yuxuan Qi, Tianao Liu, Linfeng Zhao, Ronghua Yang, Kang Ning

The paper introduces MGM2, a multimodal foundation model for microbial communities that predicts responses to interventions and interprets community changes using shared representations of molecular identity and context.

bioRxiv · Sep 30, 2026 · PreprintBioinformatics

Microbial general model: Leveraging large language model for contextualized microbiome analysis

Haohong Zhang, Yuli Zhang, Zixin Kang, Jiayun Xiong, Ronghua Yang, Kang Ning

The paper introduces MGM, a foundation model for microbiome analysis, showing improved classification and detection of dynamic patterns across diverse contexts.

Advanced Science · Jan 25, 2026Peer-reviewedBioinformatics

MicroProphet: A Digital Twin Framework for Predicting Microbial Community Dynamics with Personalized Precision

Yuli Zhang, Kouyi Zhou, Xiaoke Chen, Haohong Zhang, Jin Han, Kang Ning

MicroProphet predicts microbial community dynamics from sparse longitudinal data, enabling personalized health monitoring and intervention planning.

bioRxiv · May 8, 2025 · PreprintMicrobiology

Towards a Generative Paradigm for Large-scale Microbiome Analysis by Generative Language Model

Haohong Zhang, Zixin Kang, Yuli Zhang, Ronghua Yang, Kang Ning

This paper introduces MGM 2.0, a generative language model for microbiome analysis that uses sentence-like representations to predict microbial colonization, generate disease-specific profiles, and improve donor selection for fecal microbiota transplantation.

bioRxiv · Jan 15, 2025 · PreprintBioinformatics