BiochemistryNucleic Acids ResearchPeer-reviewed
Biochemical and Structural Characterization of Fapy·dG Replication by Human DNA Polymerase β
Shijun Gao, Peyton N. Oden, Benjamin J. Ryan…·Marc M. Greenberg
This study investigates how human DNA polymerase β processes the mutagenic lesion Fapy*dG during DNA replication, showing inefficient bypass and incorporation, suggesting mutagenicity arises from bypass rather than lesion incorporation.
4 citations