Enhancing the hyaline cartilage regenerative potential of induced pluripotent stem cell-derived chondrocyte cell sheets
Takumi Takahashi, Ryoka Uchiyama, Eriko Toyoda, Miki Maehara, Yoshiko Takahashi, Shiho Wasai, Haruka Oomura, Makoto Ogawa, Akihiro Yamashita, Masahiko Watanabe, Noriyuki Tsumaki, Masato Sato
This study demonstrates that iPS cell-derived chondrocyte sheets can regenerate hyaline cartilage in vivo when cultured under low-serum and hypoxic conditions.
bioRxiv · Sep 28, 2026 · PreprintBioengineering