Splenic tropism of Plasmodium vivax in acute infection and spleen-attenuated systemic inflammation
Steven Kho, Hasrini Rini, Noy Norman Kambuaya, Syawal Satria, Freis Candrawati, Putu A I Shanti, King Alexander, Benediktus Andries, Aisah R Amelia, Anjana Rai, Kim A. Piera, Agatha Mia Puspitasari, Ristya Amalia, Pak Prayoga, Leo Leonardo, , Nicholas M. Anstey
This study compares parasite biomass in spleen-intact and splenectomized patients with acute P. vivax malaria, finding that 89% of total-body parasite biomass is splenic.
bioRxiv · Mar 28, 2026 · PreprintPathology