Damian A. Oyong

The paper characterizes malaria-specific Tfh and Tr1 cells in a longitudinal cohort, finding overlapping phenotypes and showing their decline after transmission interruption.

This study shows that malaria exposure increases cytotoxic Vδ2+ T cell expansion in human tonsil and spleen organoids, with clonal expansion and activation, while not significantly affecting influenza vaccine responses.

This study compares parasite biomass in spleen-intact and splenectomized patients with acute P. vivax malaria, finding that 89% of total-body parasite biomass is splenic.

This study compares CD4 T cell responses to Plasmodium falciparum and P. vivax malaria, finding similar activation and proliferation but species-specific differences in peripheral Tfh cell subsets and IL-10 production.

The paper shows Vγ1+ γδ T cells produce IL-4 to activate DC and CD8 T cells, enhancing immunity against Plasmodium.

This study shows that latent cytomegalovirus infection reduces NK cell responses to Plasmodium falciparum and impairs parasite control by disrupting IL-12 production.

The paper identifies two functionally distinct Tfh1 subsets in malaria infection, showing that only CCR7pos Tfh1 and Tfh2 cells are associated with antibody development.