Comprehensive analyses of the cysteine thiol oxidation of PKM2 reveals the effects of multiple oxidation on cellular oxidative stress response
Hayato Irokawa, Satoshi Numasaki, Shin Kato, Kenta Iwai, Atsushi Inose-Maruyama, Takumi Ohdate, Gi‐Wook Hwang, Takashi Toyama, Toshihiko Watanabe, Shusuke Kuge
This study identifies oxidation-sensitive cysteine residues in PKM2 and shows their role in modulating oxidative stress response and cellular ROS levels.
Biochemical Journal · Mar 22, 2021Peer-reviewedMolecular Biology