Faf2 is required for neural differentiation in embryonic neural progenitor cells
Anneke Dixie Kakebeen, Leon Dunphy, Heather K Hazen, Lee Ann Niswander
This study shows FAF2 is essential for ER homeostasis in neural progenitor cells, and its loss causes ER stress that blocks neural differentiation despite transcriptional activation of differentiation genes.
Frontiers in Cell and Developmental Biology · Aug 26, 2026Peer-reviewedDevelopmental Biology