Heejung Shim

TRACE: a framework for traceable biomedical resource construction demonstrated through single-cell glaucoma data

TRACE provides a framework for creating traceable biomedical resources, demonstrated with a single-cell glaucoma dataset, enabling reproducible analyses and resource reuse.

Thousands of novel translated open reading frames in humans inferred by ribosome footprint profiling

This study identifies 7,273 new human coding sequences using ribosome footprint profiling and validates their functionality through selective constraint and translation correlation analysis.

A multivariate genome-wide association analysis of 10 LDL subfractions, and their response to statin treatment, in 1868 Caucasians

This study performs a genome-wide association analysis of LDL and IDL subfractions and their response to statins in 1868 individuals, identifying strong genetic associations and demonstrating increased power with multivariate analysis.

msCentipede: Modeling heterogeneity across genomic sites improves accuracy in the inference of transcription factor binding

The paper introduces msCentipede, a model that improves transcription factor binding site inference by better modeling DNase I cleavage pattern heterogeneity and spatial structure.