Estradiol treatment enhances neurovascular coupling independent of metabolic health status in a mouse model of menopause
Zachary M. T. Plumley, Jennifer Calvo Iglesias, Irene F. Ugidos, Alice Breaux Walker, Isabela Pires dos Santos, Henry Taylor, Ricardo Mostany
This study shows that estradiol treatment improves neurovascular coupling in mice regardless of their metabolic health, suggesting estrogen's benefits may not be limited by pre-existing metabolic conditions.
bioRxiv · May 21, 2025 · PreprintNeuroscience