Author

Hermann Josef Vormoor

University Medical Center Utrecht

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alicia PerzolliiD· 1 shared Bexultan KazybayiD· 1 shared Lennart A. KesteriD· 1 shared Mauricio Nicolás Ferrao BlancoiD· 1 shared Olaf T HeidenreichiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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1 shared paperCancer Biology

Alicia PerzolliORCID

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1 paper

Recent·Most cited

The bone marrow microenvironment of RAS pathway mutant B-ALL is enriched for immunosuppressive regulatory T cells

Mauricio Nicolás Ferrao Blanco, Bexultan Kazybay, Alicia Perzolli, Lennart A. Kester, Olaf T Heidenreich, Hermann Josef Vormoor

This study identifies an immunosuppressive bone marrow microenvironment in RAS-mutant B-ALL, enriched for regulatory T cells, and suggests CTLA-4 blockade could enhance T-cell-engager efficacy.

bioRxiv · Mar 18, 2026 · PreprintCancer Biology