Mauricio N. Ferrao Blanco

This study identifies an immunosuppressive bone marrow microenvironment in RAS-mutant B-ALL, enriched for regulatory T cells, and suggests CTLA-4 blockade could enhance T-cell-engager efficacy.

This study examines lymphocyte dynamics during chemotherapy in pediatric AML, finding preserved or increased lymphocytes alongside blast reduction, suggesting a potential window for BiTE therapy.

This study identifies distinct stromal cell populations in B-ALL bone marrow and shows their roles in supporting leukemic cell survival and chemoresistance.

This study combines in silico and in vitro approaches to identify drug targets for osteoarthritis by modeling chondrocyte phenotype transitions and validating predictions in cell lines.