Applying Spatial Statistics to Spatial Transcriptomics Reveals Local Association Between M2-like Macrophages and Fibrosis in Diabetic Kidney Disease
Kanako Terakawa, Hideaki Kawaguchi, Masaomi Nangaku, Imari Mimura
This paper applies geographically weighted regression to spatial transcriptomics data to identify spatially coupled M2 macrophages and fibrosis in DKD, finding enriched IgE-related genes in high-coupling spots.
bioRxiv · Jun 3, 2026 · PreprintBioinformatics