Capturing the Differences between Humoral Immunity in the Normal and Tumor Environments from Repertoire-Seq of B-Cell Receptors Using Supervised Machine Learning
Hiroki Konishi, Daisuke Komura, Hiroto Katoh, Shinichiro Atsumi, Hirotomo Koda, Asami Yamamoto, Yasuyuki Seto, Masashi Fukayama, Rui Yamaguchi, Seiya Imoto, Shumpei Ishikawa
This study uses supervised machine learning to classify BCR/Ig sequences from normal and tumor tissues, finding distinct sequence-level features between the two environments.
BMC Bioinformatics · May 28, 2019Peer-reviewedBioinformatics