Epigenomic co-localization and co-evolution reveal a key role for 5hmC as a communication hub in the chromatin network of ESCs
David Juan, Juliane Perner, Enrique Carrillo de Santa Pau, Simone Marsili, David Ochoa, Ho-Ryun Chung, Martin Vingron, Daniel Rico, Alfonso Valencia
The paper identifies 5hmC as a central hub in the chromatin network of ESCs, linking DNA demethylation to chromatin remodeling and pluripotency factors through epigenomic co-localization and co-evolution analysis.
bioRxiv · Dec 3, 2015Bioinformatics