Inactivation of NMDAR and CaMKII signaling within the prelimbic cortex blocks incubated cocaine- and sucrose-craving
Laura L. Huerta Sanchez, Natasha M. Siao, Sanil R. Chaudhari, Julie E. Barrios, Audrey Y. Na, Mirette G. Tadros, Megan L. McConnell, Rachel M. Kaplan, Caden R. Lane, Hoa H.T. Doan, Ashley B. Liger, T Chou, Serena Marcon, Fernando Camillo Santos Cano, Tod E. Kippin, Karen Kathleen Szumlinski
This study shows that blocking NMDAR and CaMKII signaling in the prelimbic cortex prevents incubated cocaine- and sucrose-craving in rats.
Neuropsychopharmacology · Jan 8, 2026Peer-reviewedNeuroscience