Model-Dependent Renal Phenotypes in Diabetic Kidney Disease: Comparative Histopathological Characterization of Commonly Used Animal Models
Raziyeh Rezaei, Azar Naimi, Yousof Gheisari, Zahra Ramazani, Issa Sulaiman Al-Amri, Hoda Doustmohammadi, Fatemeh Jamshidi‐Adegani, Sulaiman Al‐Hashmi
This study compares histopathological features of three diabetic kidney disease models, finding that Akita and STZ models show clear structural changes while db/db models require electron microscopy for accurate assessment.
bioRxiv · Jul 8, 2026 · PreprintPathology