CTHRC1+ Fibroblasts and SPP1+ Macrophages Synergistically Contribute to Pro-Tumorigenic Tumor Microenvironment in Pancreatic Ductal Adenocarcinoma
Evan Li, Hoi Ching Cheung, Shuangge Ma
This study identifies SPP1+ macrophages and CTHRC1+ fibroblasts as synergistic contributors to an immunosuppressive tumor microenvironment in PDAC, linked to poor prognosis.
Scientific Reports · Jul 29, 2024Peer-reviewedCancer Biology