Shuangge Ma

Intranasal hemagglutinin boosters after mRNA-LNP vaccination induce mucosal immunity and cross-protection against influenza A virus in mice.

This study identifies SPP1+ macrophages and CTHRC1+ fibroblasts as synergistic contributors to an immunosuppressive tumor microenvironment in PDAC, linked to poor prognosis.

HEARTSVG identifies spatially variable genes in spatial transcriptomic data with high accuracy and efficiency, uncovering biologically significant patterns in colorectal cancer.

This paper identifies sex- and KRAS-specific ferroptosis differences in CRC and explores drug repurposing for KRAS mutant tumors using multi-omics data.

The paper introduces DReSS, a method to quantify reachability differences between state spaces of Boolean networks caused by structural perturbations, and demonstrates its application in detecting sensitive interactions in yeast cell cycle regulatory networks.