A novel mechanism for morphological change during bacterial sporulation based on programmed peptidoglycan degradation
Carlos A. Ramírez Carbó, Oihane Irazoki, Srutha Venkatesan, Lauren JS Chen, Haylie A. Morales, Assariel J. Garcia Avila, Hoi-Ling Cheung, Felipe Cava, Beiyan Nan
This study identifies a novel mechanism in bacterial sporulation where programmed peptidoglycan degradation by lytic transglycosylases LtgA and LtgB controls morphological changes, preventing non-resistant pseudospore formation.
bioRxiv · Jun 26, 2025 · PreprintMicrobiology