An atlas of genetic effects on the monocyte methylome across European and African populations
Wanheng Zhang, Chuan Qiu, Xiao Zhang, Zichen Zhang, Kuan-Jui Su, Zhe Luo, Minghui Liu, Bingxin Zhao, Lang Wu, Qing Tian, Hui Shen, Chong Wu, Hong-Wen Deng
The paper constructs a multi-ancestry methylome atlas of purified monocytes, identifies population-specific methylation quantitative trait loci, and performs methylome-wide association studies for 41 traits, revealing novel associations for type 2 diabetes.
Genome Medicine · Mar 28, 2026Peer-reviewedGenetic & Genomic Medicine