HIV-1 infection of human microglia activates inflammatory pathways associated with HIV-associated neurocognitive disorders (HAND)
Jason E. Hammonds, Roy Moscona, Kathleen Candor, Hope Guthier, Rathnakumar Kumaragurubaran, Thomas Hagan, Paul W. Spearman
This study infects human microglia with HIV and identifies gene expression changes linked to HAND, showing distinct inflammatory pathways compared to macrophages.
bioRxiv · Feb 13, 2025 · PreprintMicrobiology