Glycosylated IgG antibodies contribute to the recovery of haemorrhagic fever with renal syndrome patients
Chuansong Quan, Lu Wang, Jiming Gao, Yaoni Li, Xiaoyu Xu, Houqiang Li, Zixuan Gao, Wenxu Ruan, Hongzhi Liu, Qian Li, Weijia Xing, Liqiong Zhao, Michael J. Carr, Weifeng Shi, Haifeng Hou
This study investigates IgG glycosylation patterns in HFRS patients, finding increased fucosylated IgG and decreased bisecting N-acetylglucosamine during recovery, with correlations between glycosylation and B cell subsets.
bioRxiv · Apr 11, 2025Immunology