Evolution engineering of methylotrophic E. coli enables faster growth than native methylotrophs
Liang-Yu Nieh, Frederic Y.-H. Chen, Hsin-Wei Jung, Kuan‐Yu Su, Chao-Yin Tsuei, Chun-Ting Lin, Yue-Qi Lee, James C. Liao
This study evolves methylotrophic E. coli to achieve faster growth on methanol than native methylotrophs using dynamic copy number variation.
bioRxiv · Apr 18, 2024 · PreprintSynthetic Biology