Targeted sequencing of candidate genes of dyslipidemia in Punjabi Sikhs: Population-specific rare variants in GCKR promote ectopic fat deposition
Dharambir K. Sanghera, Ruth Hopkins, Megan W. Malone-Perez, Cynthia Bejar, Chengcheng Tan, Huda J. Mussa, Paul W. Whitby, Ben Fowler, Chinthapally V. Rao, Kar-Ming A. Fung, Stan A. Lightfoot, John Kimble Frazer
The paper identifies population-specific rare variants in GCKR associated with hypertriglyceridemia and ectopic fat deposition using targeted sequencing and zebrafish models.
PLoS ONE · Aug 1, 2019Peer-reviewedGenetics