Author

John Kimble Frazer

University of Oklahoma Health Sciences CenterORCID 0000-0003-2936-2817Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:zebrafish· 3 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:imaging· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Gilseung ParkiD· 2 shared Megan W. Malone-Perez· 2 shared Ameera HasaniD· 1 shared Anna Huttenlocher AiD· 1 shared Aurora KrausiD· 1 shared Ben Fowler· 1 shared Brant M. WeinsteiniD· 1 shared Brashé Wood· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersDevelopmental Biology

Gilseung ParkORCID

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3 papers

Recent·Most cited

Developmental BiologyThe Journal of Experimental MedicinePeer-reviewedApr 1, 2025

The axillary lymphoid organ - an external, experimentally accessible immune organ in the zebrafish

Daniel Castranova, Madeleine I. Kenton, Aurora Kraus…·Brant M. Weinstein

The paper identifies a new external immune organ in zebrafish, the axillary lymphoid organ, suitable for live imaging of immune cell dynamics.

9 citationstop 5%

zebrafishimaging

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Developmental BiologyThe Journal of ImmunologyPeer-reviewedApr 24, 2024

Dynamic Changes in Lymphocyte Populations Establish Zebrafish as a Thymic Involution Model

Ameera Hasan, Jose Juan Macias, Brashé Wood…·John Kimble Frazer

This study shows zebrafish thymic B cells increase relative to T cells after involution, similar to humans, and establishes zebrafish as a model for studying thymic involution.

6 citations

zebrafishbulk RNA-seq

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GeneticsPLoS ONEPeer-reviewedAug 1, 2019

Targeted sequencing of candidate genes of dyslipidemia in Punjabi Sikhs: Population-specific rare variants in GCKR promote ectopic fat deposition

Dharambir K. Sanghera, Ruth Hopkins, Megan W. Malone-Perez…·John Kimble Frazer

The paper identifies population-specific rare variants in GCKR associated with hypertriglyceridemia and ectopic fat deposition using targeted sequencing and zebrafish models.

19 citations

zebrafishwhole-exome sequencing

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