CD59 Promotes SNARE Complex Assembly via Interaction with the Proline-Rich N-Terminal Domain of VAMP2
Hui Xiang, Yichen Liu, Jun Feng, Wenjie Wen
This study identifies the proline-rich N-terminal domain of VAMP2 as the binding site for CD59, which promotes SNARE complex assembly, and shows that point mutations in CD59 do not impair this function.
bioRxiv · Aug 6, 2026 · PreprintNeuroscience