Author

Hyunsun Lee

Broad Institute

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Genetics· 1

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Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:eQTL / molecular QTL mapping· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Aparna NathaniD· 1 shared Cristian ValenciaiD· 1 shared Joyce B. KangiD· 1 shared Laurie RumkeriD· 1 shared Soumya RaychaudhuriiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperGenetics

Aparna NathanORCID

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1 paper

Recent·Most cited

Modeling heterogeneity in single-cell perturbation states enhances detection of response eQTLs

Cristian Valencia, Aparna Nathan, Joyce B. Kang, Laurie Rumker, Hyunsun Lee, Soumya Raychaudhuri

The paper demonstrates that modeling single-cell perturbation states improves detection of reQTLs by accounting for cell-level heterogeneity in perturbation responses.

bioRxiv · Feb 20, 2024 · PreprintGenetics