Cellular senescence is a central response to cytotoxic chemotherapy in high-grade serous ovarian cancer
L. Calvo, S. Cheng, M. Skulimowski, I. Clément, L. Portelance, Y. Zhan, E. Carmona, J. Lafontaine, M. de Ladurantaye, K. Rahimi, D. Provencher, A.-M. Mes-Masson, F. Rodier
The paper shows that chemotherapy induces cellular senescence in high-grade serous ovarian cancer, which correlates with better patient survival.
bioRxiv · Sep 24, 2018 · PreprintCancer Biology