Radiosynthesis, in vitro and preliminary in vivo evaluation of the novel glutamine derived PET tracers fluorobiphenylglutamine
T. Baguet, J. Verhoeven, G. Pauwelyn, J. Hu, P. Lambe, S. De Lombaerde, S. Piron, S. Donche, B. Descamps, I. Goethals, C. Vanhove, F. De Vos, M. H. Beyzavi
This paper develops and evaluates two novel PET tracers, [18F]fluorophenylglutamine and [18F]fluorobiphenylglutamine, for imaging glutamine metabolism in tumors, showing promising in vitro and in vivo results.
bioRxiv · Feb 14, 2020Cancer Biology