Author

I. J. General

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Rinken· 1 shared A. Tobi· 1 shared E. Asciutto· 1 shared E. K. Asciutto· 1 shared K. Posnograjeva· 1 shared P. Lingasamy· 1 shared S. Kopantsuk· 1 shared S. Pantano· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 22 mutual co-author links

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1 shared paperCancer Biology

A. Rinken

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2 papers

Recent·Most cited

PL1 Peptide Engages Acidic Surfaces on Tumor-Associated Fibronectin and Tenascin Isoforms to Trigger Cellular Uptake.

P. Lingasamy, K. Posnograjeva, S. Kopantsuk, A. Tobi, A. Rinken, I. J. General, E. Asciutto, T. Teesalu

PL1 peptide binds acidic surfaces on tumor-associated Fibronectin EDB and Tenascin C-C to enable cellular uptake of functionalized nanoparticles.

bioRxiv · Sep 16, 2021Cancer Biology

Physical Interactions Driving the Activation/Inhibition of Calcium/Calmodulin Dependent Protein Kinase II

E. K. Asciutto, S. Pantano, I. J. General

The paper investigates how Ca2+/CaM binding and electrostatic interactions drive the activation/inhibition of CaMKII through molecular dynamics simulations and free energy calculations.

bioRxiv · Mar 27, 2020Biophysics