Melanocortin 1 receptor regulates cholesterol and bile acid metabolism in the liver
K. Thapa, J. J. Kadiri, K. Saukkonen, I. Pennanen, M. Cai, E. Savontaus, P. Rinne
This study shows that MC1-R in hepatocytes regulates cholesterol and bile acid metabolism, with its deficiency causing hypercholesterolemia and liver fibrosis.
bioRxiv · Nov 8, 2022Physiology