Mechanism of strand displacement DNA synthesis by the coordinated activities of human mitochondrial DNA polymerase and SSB
I. Plaza-G.A., K. M. Lemishko, R. Crespo, T. Q. Truong, L. S. Kaguni, F. J. Cao-Garcia, G. L. Ciesielski, B. Ibarra
This study investigates how human mitochondrial DNA polymerase Pol{gamma} and SSBs coordinate to enable strand displacement DNA synthesis, revealing mechanisms that enhance polymerase activity.
bioRxiv · Jul 19, 2022Biophysics