Exploring the conformational changes of the Munc18-1/syntaxin 1a complex
I. Stefani, J. Iwaszkiewicz, D. Fasshauer
The paper investigates how Munc18-1 induces conformational changes in syntaxin-1a to facilitate SNARE complex formation, using mutations, structural analysis, and molecular dynamics simulations.
bioRxiv · Nov 29, 2022Biochemistry