Cell BiologybioRxivPreprint
KaryoCreate: a new CRISPR-based technology to generate chromosome-specific aneuploidy by targeting human centromeres
N. Bosco, A. Goldberg, A. F. Johnson…·T. Davoli
KaryoCreate generates chromosome-specific aneuploidy by targeting centromeres with CRISPR, showing it can induce gains or losses of targeted chromosomes in human cells.
DOI 10.1101/2022.09.27.509580