Author

A. Goldberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 4 Biophysics· 1 Cell Biology· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:statistical model· 4 Research Focus:chromatin & epigenetic regulation· 3 Assay:whole-genome sequencing· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1 Research Focus:ecology & biodiversity· 1

Frequent Co-Authors

N. A. Rosenberg· 2 shared S. Beleza· 2 shared A. F. Johnson· 1 shared A. M. Mychajliw· 1 shared A. Mermerian· 1 shared A. Rastogi· 1 shared B. Xie· 1 shared C. A. Gionco· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersEvolutionary Biology

N. A. Rosenberg

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

The molecular mechanism of positive allosteric modulation at the dopamine D1 receptor

A. Goldberg, B. Xie, L. Shi

This study investigates the molecular mechanism of LY3154207's positive allosteric modulation at the dopamine D1 receptor using cryo-EM structures and molecular dynamics simulations.

bioRxiv · Jul 27, 2023Biophysics

KaryoCreate: a new CRISPR-based technology to generate chromosome-specific aneuploidy by targeting human centromeres

N. Bosco, A. Goldberg, A. F. Johnson, X. Zhao, J. C. Mays, P. Cheng, J. J. Bianchi, C. Toscani, L. Katsnelson, D. Annuar, S. Mei, R. E. Faitelson, I. Y. Pesselev, K. S. Mohamed, A. Mermerian, , T. Davoli

KaryoCreate generates chromosome-specific aneuploidy by targeting centromeres with CRISPR, showing it can induce gains or losses of targeted chromosomes in human cells.

bioRxiv · Sep 27, 2022 · PreprintCell Biology

Sex-biased admixture and assortative mating shape genetic variation and influence demographic inference in admixed Cabo Verdeans

K. L. Korunes, G. B. Soares-Souza, K. Bobrek, H. Tang, I. I. Araujo, A. Goldberg, S. Beleza

This study examines genetic variation in Cabo Verdeans to show how sex-biased admixture and non-random mating affect demographic inference and genomic patterns.

G3 Genes|Genomes|Genetics · Jul 21, 2022Peer-reviewedEvolutionary Biology

Rapid adaptation to malaria facilitated by admixture in the human population of Cabo Verde

I. Hamid, K. Korunes, S. Beleza, A. Goldberg

The paper shows that admixture in Cabo Verde facilitated rapid adaptation to malaria with a high selection coefficient.

bioRxiv · Sep 1, 2020Evolutionary Biology

7,000 years of turnover: historical contingency and human niche construction shape the Caribbean's Anthropocene biota

M. E. Kemp, A. M. Mychajliw, J. Wadman, A. Goldberg

The paper analyzes 7,000 years of species introductions in the Caribbean to show how human colonization and cultural practices shaped biodiversity and conservation outcomes.

bioRxiv · Mar 5, 2020Ecology

Assortative mating and the dynamical decoupling of genetic admixture levels from phenotypes that differ between source populations

J. Kim, M. D. Edge, A. Goldberg, N. A. Rosenberg

The paper develops a model showing how genetic admixture and phenotypes decouple over time, especially with assortative mating and few genetic loci influencing the trait.

bioRxiv · Sep 20, 2019Evolutionary Biology

Assortative mating by population of origin in a mechanistic model of admixture

A. Goldberg, A. Rastogi, N. A. Rosenberg

This paper develops a mechanistic model to study ancestry-assortative mating in admixed populations and shows how it affects admixture fraction variance.

bioRxiv · Aug 21, 2019Evolutionary Biology