Live imaging of the co-translational recruitment of XBP1 mRNA to the ER and its processing by diffuse, non-polarized IRE1a.
S. Gomez-Puerta, R. Ferrero, T. Hochstoeger, I. Zubiri, J. A. Chao, T. Aragon, F. Voigt
The paper uses live imaging to show XBP1 mRNA is recruited to the ER and processed by IRE1a, without forming large IRE1 clusters.
bioRxiv · Nov 15, 2021Cell Biology