Author

Iain C Macaulay

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:zebrafish· 1

Frequent Co-Authors

Ana CvejiciD· 2 shared Sarah A Teichmann· 2 shared Charlotte Labalette· 1 shared David Gfeller· 1 shared Kedar N Natarajan· 1 shared Lam-Ha Ly· 1 shared Lauren Ferreira· 1 shared Michael J.T. Stubbington· 1 shared

Activity by Year

2016-2017 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

Ana CvejicORCID

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2 papers

Recent·Most cited

Single-cell transcriptome analysis of fish immune cells provides insight into the evolution of vertebrate immunity

Santiago J Carmona, Sarah A Teichmann, Lauren Ferreira, Iain C Macaulay, Michael J.T. Stubbington, Ana Cvejic, David Gfeller

The paper analyzes immune cell transcriptomes across vertebrates to reveal evolutionary patterns in gene conservation and turnover, finding higher gene turnover in NK cells compared to T cells.

Genome Research · Jan 13, 2017Peer-reviewedImmunology

Power Analysis of Single Cell RNA‐Sequencing Experiments

Valentine Svensson, Kedar N Natarajan, Lam-Ha Ly, Ricardo J Miragaia, Charlotte Labalette, Iain C Macaulay, Ana Cvejic, Sarah A Teichmann

This paper evaluates the sensitivity and accuracy of scRNA-seq protocols using spike-ins and a standardized pipeline, comparing sequencing depth trade-offs and RNA degradation effects.

bioRxiv · Sep 8, 2016Genomics