An agent-based modelling framework for tumour growth incorporating mechanical and evolutionary aspects of cell dynamics
Cicely K. Macnamara, Ignacio Ramis-Conde, Tommaso Lorenzi, Alfonso Caiazzo
This paper develops an agent-based model of tumor growth that integrates mechanical and evolutionary dynamics, showing phenotypic heterogeneity arises from oxygen distribution inhomogeneities.
bioRxiv · May 30, 2024 · PreprintCancer Biology