Multimodal layer modelling reveals in-vivo pathology in ALS
Alicia Northall, Juliane Doehler, Miriam Weber, Igor Tellez, Susanne Petri, Johannes Prudlo, Stefan Vielhaber, Stefanie Schreiber, Esther Kuehn
This study uses 7T-MRI and multimodal layer modeling to identify layer-specific pathology in early-stage ALS patients, revealing distinct iron and calcium accumulation patterns and their relationship to demyelination.
bioRxiv · Jun 28, 2023 · PreprintNeuroscience