Perinatal Asphyxia Alters Physiological Responses and Ex Vivo Cardiovascular Function of Preterm Growth-Restricted Lambs
Zahrah Azman, Beth R. Piscopo, Amy E. Sutherland, Alison M. Thiel, Valerie A. Zahra, Yen Pham, Ilias Nitsos, Mumu Mahjabin Hossain, Atul Malhotra, Stephanie Miller, Kristen J. Bubb, Graeme R. Polglase, Beth J. Allison
This study shows that preterm growth-restricted lambs have altered cardiovascular responses to perinatal asphyxia, including impaired vascular contractility and dysregulated adrenergic receptor function.
bioRxiv · May 27, 2025 · PreprintPhysiology