Human PRE-PIK3C2B exhibits long-range intra- and inter-chromosomal interactions with genomic regions enriched in repressive marks.
Jayant Maini, Ankit Kumar Pathak, Kausik Bhattacharyya, Narendra Kumar, Ankita Narang, N. F. Jain, Inderpreet Singh, Vanika Dhingra, Vani Brahmachari
The paper identifies long-range chromatin interactions of the PRE-PIK3C2B region using 4C-Seq and validates them with 3C-PCR, showing enrichment of repressive marks and association with LINE/SINE repeats.
bioRxiv · Nov 11, 2020 · PreprintGenetics