Indu Mithra Madhuranthakam

Differences between males and females in psychostimulant/sucrose self-administration (when observed) may not necessarily be driven by biological sex.

This study validates the MISSING model by showing that sex differences in drug self-administration may arise from individual variability rather than biological sex.

The recreational-to-habitual shift in psychostimulant use is an economic demand parameter that is unrelated to drug consumption levels (under normal and punishment conditions).

The study develops a behavioral economic model to assess the recreational-to-habitual shift in drug use and finds it is unrelated to drug intake under normal and punishment conditions.

A Challenge To The Assumption That Short- versus Long-Access Groups of Opioid Users Represent Distinct Phenotypes

The paper tests whether opioid user groups defined by access conditions represent distinct phenotypes using CENTERED clustering, finding they are mixtures of different user types.

Experience-dependent sex differences in the role of dorsal striatal dopamine D1 receptor activity in methamphetamine self-administration revealed by a novel TREND model.

The paper introduces a novel TREND model to detect experience-dependent sex differences in the role of dorsal striatal dopamine D1 receptor systems in methamphetamine self-administration, finding that TREND outperforms existing models in this task.