Author

Iona M MacLeod

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Genetics· 1

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Research Focus:genome assembly· 1 Research Focus:GWAS / association mapping· 1 Organism:human· 1 Approach:mixed model· 1 Research Focus:polygenic risk· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

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Alkes L Price· 1 shared Ben J Hayes· 1 shared Bonnie Berger· 1 shared George Tucker· 1 shared Michael E Goddard· 1 shared Po-Ru LohiD· 1 shared

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2015-2015 · peak 1/yr

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1 shared paperGenetics

Alkes L Price

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1 paper

Recent·Most cited

Two variance component model improves genetic prediction in family data sets

George Tucker, Po-Ru Loh, Iona M MacLeod, Ben J Hayes, Michael E Goddard, Bonnie Berger, Alkes L Price

This paper introduces a two variance component model that improves genetic prediction in family data by jointly modeling IBS sharing and pedigree structure, achieving higher prediction accuracy and correcting inflated test statistics.

bioRxiv · Jun 10, 2015 · PreprintGenetics