Bonnie Berger

Sequence biases in CLIP experimental data are incorporated in protein RNA-binding models

The paper identifies a bias in CLIP data caused by cleaving enzyme specificity, which affects protein RNA-binding models like GraphProt.

Fast genotyping of known SNPs through approximate k-mer matching

LAVA is a fast and accurate SNP genotyping method using approximate k-mer matching, outperforming existing pipelines in speed and accuracy for dbSNP and Affymetrix SNPs.

Calibrating the Human Mutation Rate via Ancestral Recombination Density in Diploid Genomes

This paper estimates the human mutation rate by analyzing recombination density in diploid genomes, finding a rate between pedigree-based and phylogenetic estimates.

Two variance component model improves genetic prediction in family data sets

This paper introduces a two variance component model that improves genetic prediction in family data by jointly modeling IBS sharing and pedigree structure, achieving higher prediction accuracy and correcting inflated test statistics.

Efficient Bayesian mixed model analysis increases association power in large cohorts

BOLT-LMM improves genetic association power in large cohorts by using a Bayesian mixture prior to model non-infinitesimal genetic architectures more realistically.

Ancient human genomes suggest three ancestral populations for present-day Europeans

The paper analyzes ancient genomes to show present-day Europeans derive from three populations: WHG, ANE, and EEF, with EEF having Basal Eurasian ancestry.

Reconstructing Austronesian population history in Island Southeast Asia

This study reconstructs Austronesian population history in Island Southeast Asia using genome-wide data, revealing unexpected ancestry links to Austro-Asiatic populations.