Cooperativity and Conformational Rearrangements in Protein-Protein and Protein-Ligand Interactions
Dinesh Thiyagaraj, Alessandro Del Re, Quan Duc Pham, Irene Gomez Garrote, Ahmad Saudi, Oleh Fedorych
The paper investigates biotin binding to streptavidin and avidin, showing two distinct energetic regimes and long-range intermolecular interactions.
bioRxiv · Jul 18, 2026 · PreprintBiophysics