Mathematical Modeling of the Canonical Aryl Hydrocarbon Receptor Pathway
Vincent Wieland, Tobias Blum, Irina Iriady, Laia Reverte-Salisa, Dilan Pathirana, Irmgard Foerster, Heike Weighardt, Jan Hasenauer
The paper develops a mathematical model of the canonical AhR pathway to identify which biochemical steps drive ligand-specific transcriptional responses using qPCR data from mouse macrophages.
bioRxiv · May 8, 2026 · PreprintSystems Biology