Author

Isaac Joshua

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:eQTL / molecular QTL mapping· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Agnieszka D’Antonio‐ChronowskaiD· 1 shared Akshay PujariiD· 1 shared Alberto Vitari· 1 shared Alex Laslavic· 1 shared Angelina McCarron· 1 shared Angelo D. Arias· 1 shared Anja Sandholm· 1 shared Athanasia D. PanopoulosiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Agnieszka D’Antonio‐ChronowskaORCID

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Author profile →

2 papers

Recent·Most cited

Uncovering senescent fibroblast heterogeneity connects DNA damage response to idiopathic pulmonary fibrosis

Jun‐Wei B. Hughes, Akshay Pujari, Anja Sandholm, Duncan Croll, Lea B. Monk, Isaac Joshua, Rachel Butterfield, Corrigan Horton, Kevin Schneider, Fiona Senchyna, Ian Brown, Zhixin A. Zhang, T. Ho, Tsung-Che Ho, Hideto Deguchi, , Judith Campisi

The paper identifies senescent fibroblast heterogeneity in IPF and links it to DNA damage response dysregulation using gene expression analysis.

npj Aging · Jun 18, 2026Peer-reviewedCell Biology

Multi-omic QTL mapping in early developmental tissues reveals phenotypic and temporal complexity of regulatory variants underlying GWAS loci

Timothy D. Arthur, Jennifer Nguyen, Benjamin A. Henson, Agnieszka D’Antonio‐Chronowska, Jeff Jaureguy, Nayara Silva, Angelo D. Arias, Paola Benaglio, W. Travis Berggren, Victor Borja, Megan Cook, Christopher DeBoever, Kenneth E. Diffenderfer, Margaret K.R. Donovan, KathyJean Farnam, , Kelly A. Frazer

The paper identifies multi-omic QTLs in early developmental tissues and shows that GWAS loci often involve complex regulatory variants not captured by eQTLs alone.

Cell Genomics · Feb 21, 2025Peer-reviewedGenomics